请使用支持JavaScript的浏览器!
主营:抗癌化学试剂和激酶抑制剂
℡ 4000-520-616
℡ 4000-520-616
MedKoo/AZD-2932featured/10mg/401120
产品编号:401120
市  场 价:¥3000.00
场      地:美国(厂家直采)
产品分类: 蛋白类>多肽>多肽合成>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$150.00
品      牌: MedKoo
公      司:MedKoo Biosciences, Inc
公司分类:
MedKoo/AZD-2932featured/10mg/401120
商品介绍

AZD-2932
featured

WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#:401120

CAS#:883986-34-3

Description:AZD-2932 is a high affinity inhibitor of VEFGR-2 and PDGFR. AZD-2932 has a balanced ~ 1:1 ratio of activity vs both VEGFR-2 and PDGFRβ and shows IC50 values of 8 and 4 nM against the two enzymes, respectively. It is also active on c-Kit and FLT3 with good selectivity on a panel of kinases. The pharmacokinetic behavior and the preclinical antitumor activity in nude mice bearing C6 rat glial tumors indicate that 31 has the potential to become an antiangiogenic agent in the clinic.

Price and Availability

SizePriceShipping out timeQuantity
10mgUSD 1502 Weeks
25mgUSD 2502 Weeks
50mgUSD 4502 Weeks
100mgUSD 6502 Weeks
200mgUSD 9502 Weeks
500mgUSD 16502 Weeks
1gUSD 28502 Weeks
2gUSD 44502 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-01-23.Prices are subject to change without notice.

AZD-2932, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 401120Name: AZD-2932CAS#: 883986-34-3Chemical Formula: C24H25N5O4Exact Mass: 447.19065Molecular Weight: 447.49Elemental Analysis: C, 64.42; H, 5.63; N, 15.65; O, 14.30

Synonym:AZD2932; AZD 2932; AZD-2932

IUPAC/Chemical Name:2-(4-((6,7-dimethoxyquinazolin-4-yl)oxy)phenyl)-N-(1-isopropyl-1H-pyrazol-4-yl)acetamide

InChi Key:TWYCZJMOEMMCGC-UHFFFAOYSA-N

InChi Code:InChI=1S/C24H25N5O4/c1-15(2)29-13-17(12-27-29)28-23(30)9-16-5-7-18(8-6-16)33-24-19-10-21(31-3)22(32-4)11-20(19)25-14-26-24/h5-8,10-15H,9H2,1-4H3,(H,28,30)

SMILES Code:O=C(NC1=CN(C(C)C)N=C1)CC2=CC=C(OC3=C4C=C(OC)C(OC)=CC4=NC=N3)C=C2

Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001

Additional Information

References

1: Plé PA, Jung F, Ashton S, Hennequin L, Laine R,Morgentin R, Pasquet G, Taylor S. Discovery of AZD2932, a newQuinazoline Ether Inhibitor with high affinity for VEGFR-2 and PDGFRtyrosine kinases. Bioorg Med Chem Lett. 2012 Jan 1;22(1):262-6. doi:10.1016/j.bmcl.2011.11.019. Epub 2011 Nov 12. PubMed PMID: 22153662.

品牌介绍
MedKoo,由化学家和药学家陈清奇博士。北卡罗莱纳州的研究三角区(Research Triangle Park, 简称 RTP ),是一家以研发、生产和销售小分子抗癌化合物为主的医药科技公司,该公司的业务范围主要是为全球所有从事抗癌药物研究和开发的制药公司,高校,研究院所,政府相关机构提供与抗癌药物分子相关的产品、试剂和技术服务。
中文名MedKoo中    文美帝药库医药科技公司创立于2008年总部位于美国东海岸
自营商城图标
厂家直采
全球直采 正品优价
正品保障图标
正品保障
厂家直发 有线跟踪
解放采购图标
正规清关
CIF100%正规报关,提供发票
及时交付图标
及时交付
限时必达 不达必赔