Tenovin-1

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WARNING: This product is for research use only, not for human or veterinary use.

Description:Tenovin-1 is a p53 activator that protects against MDM2-mediated p53 degradation.

Price and Availability

Tenovin-1 purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).

Chemical Structure

Theoretical Analysis

MedKoo Cat#: 406723Name: Tenovin-1CAS#: 380315-80-0Chemical Formula: C20H23N3O2SExact Mass: 369.1511Molecular Weight: 369.48052Elemental Analysis: C, 65.01; H, 6.27; N, 11.37; O, 8.66; S, 8.68

Synonym:Tenovin1

IUPAC/Chemical Name:N -[[[4-(Acetylamino)phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide

InChi Key:WOWJIWFCOPZFGV-UHFFFAOYSA-N

InChi Code:InChI=1S/C20H23N3O2S/c1-13(24)21-16-9-11-17(12-10-16)22-19(26)23-18(25)14-5-7-15(8-6-14)20(2,3)4/h5-12H,1-4H3,(H,21,24)(H2,22,23,25,26)

SMILES Code:O=C(NC(NC1=CC=C(NC(C)=O)C=C1)=S)C2=CC=C(C(C)(C)C)C=C2

Technical Data

Additional Information

References

1: Lain S, Hollick JJ, Campbell J, Staples OD,Higgins M, Aoubala M, McCarthy A,  Appleyard V, Murray KE, Baker L,Thompson A, Mathers J, Holland SJ, Stark MJ, Pass G, Woods J, Lane DP,Westwood NJ. Discovery, in vivo activity, and mechanism of action of asmall-molecule p53 activator. Cancer Cell. 2008 May;13(5):454-63. doi: 10.1016/j.ccr.2008.03.004. PubMed PMID: 18455128; PubMed CentralPMCID: PMC2742717.